Afterword: I have been a Easterm medicine doctor for 37 years, having 13 generations working in medicine; when translating and writing with Dr.Do Van Loc, this article does not mean that the Oriental Medicine doctor declaresthe oriental medicine but only wishes that we still need to be vigilant about the drug with all out responsibilities before the human’s life.

Although herbal medincines in traditional oriental medicine have long been considered to be relative safe and often non-toxic and in university lectures, ancient books have been classified, specify those drugs that ca be toxic even when used in the right dogsage. But with the 4.0 era, when cosidering physicians and remedies interacting with the body at the molecular biology level, the physician’s caution must increase.

Whether or not toxins in traditional medicine

Toxins from herbs may be toxins available in herbs or from external contamination or from preparation or all three. It has been reported that about 10% of end-stage diabetic kidney disease in Taiwan is caused by herbal remedies. It is also harmful to the kidneys to cause genetic mutations and cancer. Aristolochiaceae family is the family of Nam nhac that includes Te Tan, Phong Ky, Ma huong, Ma horse, Tam phong, Son duong, not to mention the pine of Lardizabalaceae, cat beard ... have diuretic effect. strong but also harmful to the kidneys ...

Although Aristolochic acid is well known to be toxic to the kidneys, some herbal medicines still contain ingredients related to this compound. The pathogenesis of kidney disease caused by the aristolochic acid toxin - aristolochic acid induced nephropathy - has the characteristic of widespread fibrous interstitial interstitial tissue and renal tubular atrophy, while glomerular damage is not evident. Urinary tract diseases commonly observed are long-term disability related to kidney disease caused by aristolochic acid toxin.

A retrospective study of 86 patients with aristolochic acid nephropathy found that 19 patients (22.0%) had acute kidney damage while 67 patients (78%) had end-stage renal disease. chronic. 11 patients (57.9%) with acute kidney damage recovered normal kidney function and 27 patients (40.2%) with chronic end-stage renal disease progressed to end-stage renal disease.

Some of the herbs in traditional Chinese medicine include: Dioscorea bulbifera, Trichosanthes kirilowii, Melia toosendan, Phan cholera (Cassia angustifolia) and Red-knotweed (Red Polygonum multiflorum) is known as a liver toxin. Hepatotoxins caused by traditional Chinese herbal medicine usually appear after 1 to 4 weeks of treatment with clinical manifestations such as fatigue, jaundice and loss of appetite. Hematopoietic toxicity is related to herbs such as Sinomeninum acutum, Mercury sulfide and Psychotria rubra. These herbs cause thrombocytopenia and hemolytic anemia . However, these side effects are uncommon and occur mostly in patients who are vulnerable to long-term and overdose herbs.

In addition, external intoxication such as arsenic, mercury, lead salts, or herbal remedies also causes serious adverse interactions between synthetic and herbal drugs, leading to complications due to increase or decrease. Toxic and pharmacological effects of each ingredient. For example, the herbs in traditional medicine used to reduce the glucose level in diabetes also co-reduce blood sugar with chemically derived medicines. There have been reports that bleeding complications can occur when used in combination with warfarin with Angelica sinensis (Oliv.) Diels or with Salvia mitiorrhiza Bunge. Physicians when prescribing to patients should be aware of this harmful mutual effect when used in combination with herbal medicines.

A number of other drugs can be toxic to symptoms of digestion, neurology such as winter Prunus persica Stokes (Persica vulgaris Mill) commonly used to treat arthritis.

Some other drugs such as Cao python (processed products from meat and python bones), blood of the turtle, gradually erectile dysfunction, erect penis does not erect, soft does not soft, sexual activity is long but not good quality, after a period of time it will completely paralyze, losing complete sexual desire, the testicles retract into the abdominal cavity

Mountainous people use Moschus moschiferus L. Cervidae temporary anti-conception musk or Po tree to destroy the ovaries, resulting in stopping female reproductive.

Although traditional medicines including traditional Chinese and traditional medicines cause less poisoning, doctors should also exercise great caution.

Translation, editing and writing
Dr. Do Van Loc and Dr. Hoang Sam

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